Circulating Tumor Cell and Cell-free Circulating Tumor DNA in Lung Cancer
نویسندگان
چکیده
منابع مشابه
Circulating Tumor Cell and Cell-free Circulating Tumor DNA in Lung Cancer
Circulating tumor cells (CTCs) are tumor cells that are separated from the primary site or metastatic lesion and disseminate in blood circulation. CTCs are considered to be part of the long process of cancer metastasis. As a 'liquid biopsy', CTC molecular examination and investigation of single cancer cells create an important opportunity for providing an understanding of cancer biology and the...
متن کاملCell-free circulating tumor DNA in cancer.
Cancer is a common cause of death worldwide. Despite significant advances in cancer treatments, the morbidity and mortality are still enormous. Tumor heterogeneity, especially intratumoral heterogeneity, is a significant reason underlying difficulties in tumor treatment and failure of a number of current therapeutic modalities, even of molecularly targeted therapies. The development of a virtua...
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Limited understanding of ovarian cancer (OC) genome portrait has hindered the therapeutic advances. The serial monitoring of tumor genotypes is becoming increasingly attainable with circulating cell-free DNA (cf-DNA) and circulating tumor cells (CTCs) emerging as "liquid biopsies". They represent non-invasive biomarkers and are viable, as they can be isolated from human plasma, serum and other ...
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AIM This pilot study assessed correlations between circulating tumor cells (CTCs) and circulating free DNA (cfDNA) of metastatic non-small cell lung cancer (NSCLC) after acquisition of resistance to epidermal growth factor receptor tyrosine kinase inhibitors. PATIENTS AND METHODS CTCs were counted using the CellSearch system (Veridex). cfDNA was analyzed for EGFR mutation status by the Cyclea...
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Urothelial carcinoma of the bladder (UCB) is a complex disease, which is associated with highly aggressive tumor biologic behavior, especially in patients with muscle-invasive and advanced tumors. Despite multimodal therapy options including surgery, radiotherapy and chemotherapy, UCB patients frequently suffer from poor clinical outcome. Indeed, the potential of diverse opportunities for moder...
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ژورنال
عنوان ژورنال: Chonnam Medical Journal
سال: 2016
ISSN: 2233-7385,2233-7393
DOI: 10.4068/cmj.2016.52.3.151